If is a closed oriented connected 3-Manifold such that every simple closed curve in lies interior to a Ball in , then is Homeomorphic with the Hypersphere, .
See also Ball, Hypersphere
References
Bing, R. H. ``Necessary and Sufficient Conditions that a 3-Manifold be .'' Ann. Math. 68, 17-37,
1958.
Rolfsen, D. Knots and Links. Wilmington, DE: Publish or Perish Press, pp. 251-257, 1976.